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The fourteenth edition includes new research on and coverage of: the scope of the opioid epidemic in the United States, and new drugs used to treat opioid dependence and opioid overdose; therapeutic uses of drugs commonly characterized as recreational, including marijuana to treat Alzheimer’s, PTSD, and epilepsy; hallucinogenics for the treatment of multiple psychiatric disorders; and ketamine for the treatment of depression; Cannabidiol (CBD) and its therapeutic uses; synthetic drugs including synthetic cannabinoids (Spice and K2), fentanyl derivatives, and bath salts; smoking and mental health; the use of genetic testing to predict the efficacy of antidepressants; the effects of e-cigarettes, their use in smoking cessation, and among young people; the effects of persistent marijuana, alcohol, and stimulant use in adolescence; the efficacy of antipsychotics to treat dementia, Parkinson’s, bipolar, OCD, and PTSD.
